王婧，1980年生，籍贯北京，北京协和医学院教师发展中心主任，中国医学科学院基础医学研究所副所院长，病理生理学系副主任。病理学博士，博士生导师，研究员。2004年毕业于北京大学医学部，2009年获美国罗彻斯特大学病理学博士学位，同年进入美国哈佛大学医学院布莱根妇女医院从事博士后研究。2012年晋升为哈佛医学院讲师。2014年作为中国医学科学院基础医学研究所“引进人才”回国。2021年入选国家级重大人才项目（教育部）。

主要从事心肺血管及相关疾病（肺动脉高压，动脉粥样硬化，高血压，腹主动脉瘤）的病理机制，分子诊断和治疗方法的研究。从分子、细胞水平阐述炎症在心肺血管相关疾病的发生发展过程中的作用，寻找诊疗新靶点。

1. Li Z#, Feng Y, Liu H, Yang H, Li J, Zhou Y, Pang J, Yang P, Zhao H*,Wang J*. Single-cell transcriptomics of mouse lung reveal inflammatory memory neutrophilsin allergic asthma. Allergy. 2022 Mar 21. (IF=13.1)

2. Ge W#, Guo X#, Song X,Pang J, Zou X,Liu Y, Niu Y, Li Z,Gao R*, Zhao H*, Wang J*. The role of immunoglobulin E and mast cells in hypertension. Cardiovasc Res. 2022 Jan 20:cvac010. (IF=10.8)

3. Zhao H#, Yang H#,Geng C#, Chen Y, Pang J, Shu T, Zhao M, Tang Y, Li B,Li Z, Hou C, Song X, Wu A, Guo X,Chen S,Liu B, Yan C*, and Wang J*, Role of IgE-FcεR1 in Pathological Cardiac Remodeling and Dysfunction. Circulation. 2021. Mar 9;143(10):1014-1030. (IF=29.7)

4. Feng Y#, Song X#, Huang Y#, Deng W, Li M, Guo X, Qin C, Tong W, Liu J*, Wang J*. SARS-CoV-2 leads to myocardial injury in rhesus macaque. Signal Transduct Target Ther. 2021 Sep 6;6(1):338. (IF=18.2)

5. Song X#, Zou X#, Ge W, Hou C, Cao Z, Zhao H, Zhang T, Jin L, Fu Y, Kong W, Yan C, Cai J, Wang J*. Blocking FcγRIIB in smooth muscle cells reduces hypertension. Circ. Res.. 2021, May 13. (IF=17.4)

6. Zhang C#, Zhao H#, Cai Y, Xiong J, Army Mohan, Lou D,Shi H, Zhang Y, Long X, Wang J*, Yan C*, Cyclic Phosphodiesterase 1C contributes to Abdominal Aortic Aneurysm. Proc Natl Acad Sci USA. 2021 Aug 3;118(31): e2107898118. (IF=11.2)

7. Liu J, Yang C, Liu T, Deng Z, Fang W, Zhang X, Li J, Huang Q, Liu C, Wang Y, Yang D, Sukhova GK, Lindholt JS, Diederichsen A, Rasmussen LM, Li D, Newton G,Luscinskas FW, Liu L, Libby P, Wang J*, Guo J*, Shi GP*. Eosinophils improvecardiac function after myocardial infarction. Nat Commun. 2020 Dec16;11(1):6396. (IF=14.9)                      

8. Wang J#, Sun C#, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP*. Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter. Nat Med. 2015 Jul;21(7):820-6. (IF=27.4)

9. Wang J#, Lindholt JS, Sukhova GK, Shi MA, Xia M, Chen H, Xiang M, He A, Wang Y, Xiong N, Libby P, Wang JA*, Shi GP*. IgE actions on CD4+ T cells, mast cells,and macrophages participate in the pathogenesis of experimental abdominal aortic aneurysms. EMBO Mol Med. 2014 Jul;6(7):952-69. (IF=8.2)

10. Wang J#, Cheng X#, Xiang M#, Kinnunen M, Wang J, Chen H, He A, Sun X, Lin Y, Tang TT, Tu X, Sjoberg S , Sukhova G, Liao YH, Conrad D, Yu LY, Kawakami T, Kovanen P, Libby P, Shi GP*. IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe–/– mice. J Clin Invest., 2011 Sep;121(9):3564-77. (IF=14.8,C100)